Hypertension is a substantial and growing global health problem, affecting 972 million people worldwide, according to a study published in the journal Lancet. Despite focused efforts and the introduction of multiple new therapies, a significant portion of hypertension patients lack blood pressure control. Research suggests that 28 percent of treated hypertensive individuals are considered resistant to treatment, the American Heart Association says. Treatment-resistant hypertension (rHTN) is an especially dangerous chronic disease because of its association with increased cardiovascular risk, including stroke and heart attack. Results from a large, international survey on rHTN found that the condition takes a significant toll on a person’s quality of life, both physically and emotionally. Below are facts and figures about the far-reaching impact of rHTN.