U.S. Senator Edward M. Kennedy of Massachusetts, the last surviving brother in a political dynasty and one of the most influential senators in history, died Tuesday night at his home on Cape Cod after a yearlong struggle with brain cancer. He was 77.
In nearly 50 years in the Senate, Kennedy, a liberal Democrat, served alongside 10 presidents — his brother John Fitzgerald Kennedy among them — compiling an impressive list of legislative achievements on health care, civil rights, education, immigration and more.
His only run for the White House ended in defeat in 1980, when President Jimmy Carter turned back his challenge for the party's nomination.